Halide ions as chemical probes for NMR studies of proteins.

نویسندگان

  • T R Stengle
  • J D Baldeschwieler
چکیده

11 Stevens, B., Spectrochim. Acta, 18, 439 (1962). 12Ferguson, J., J. Chem. Phys., to be published. 13 Abbreviations for the synthetic polynucleotides and their hydrogen-bonded states are those of Inman, R. B., and R. L. Baldwin, J. Mol. Biol., 5, 172 (1962). 14 Davidson, N., J. Widholm, U. S. Nandi, R. Jensen, B. M. Olivera, and J. C. Wang, these PROCEEDINGS, 53, 111 (1965). 11 Chamberlin, M. J., and D. L. Patterson, J. Mol. Biol., 12, 410 (1965). 16 Warshaw, M. M., and I. Tinoco, J. Mol. Biol., 13, 54 (1965). 17 Fasman, G. D., C. Lindblow, and L. Grossman, Biochemistry, 3, 1015 (1964). 18Longworth, J. W., R. 0. Rahn, and R. G. Shulman, unpublished data.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Functionalization of nine-atom deltahedral Zintl ions with organic substituents: detailed studies of the reactions.

Presented are the results of a systematic investigation of the reactions of nine-atom deltahedral clusters of germanium (Zintl ions, Ge(9)(n-)) with alkynes and alkyl halides that result in alkenylation and alkylation of the clusters, respectively. The reaction pathways have been probed in depth using various, appropriately substituted alkynes and organic halides, including some typical mechani...

متن کامل

NMR studies of lysozyme surface accessibility by using different paramagnetic relaxation probes.

Paramagnetic probes, whose approach to proteins can be monitored by nuclear magnetic resonance (NMR) studies, have been found to be of primary relevance for investigating protein surfaces' accessibility. Here, a Gd(III) neutral complex which contains two metal ions, [Gd2(L7)(H2O)2], is suggested as a paramagnetic probe particularly suited for systematic NMR investigation of protein surface acce...

متن کامل

Design of a hyperpolarized (15)N NMR probe that induces a large chemical-shift change upon binding of calcium ions.

Ca(2+) is a fundamental metal ion for physiological functioning. Therefore, molecular probes for Ca(2+) analysis are required. Recently, a hyperpolarized NMR probe has emerged as a promising tool. Here, we report a new design of a hyperpolarized NMR probe for Ca(2+), which showed a large chemical shift change upon binding to Ca(2+) and was applied for Ca(2+) sensing in a hyperpolarized state.

متن کامل

A Biotechnological Perspective on The Affinity Magnetic Separation and Purification Based on Oligonucleotides

The rapidly growing field of biotechnology has created a critical need for simple, fast andhigh-throughput processes for the separation and purification of biomolecules from biologicalmatrices. In recent years, several bioseparation techniques have been proposed as advancedalternatives to the classical separation methods. These modern processes emphasize ultrahighselective and sensitive analysi...

متن کامل

Analysis of key steps in the catalytic cross-coupling of alkyl electrophiles under Negishi-like conditions.

The use of tpy'(tpy'= 4,4',4''-tri-tert-butyl-terpyridine) as a ligand for nickel allows for the isolation of a Ni(I)-alkyl complex and a Ni(II)-alkyl halide complex, both of which can be used as mechanistic probes of key steps in alkyl cross-coupling reactions.

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Proceedings of the National Academy of Sciences of the United States of America

دوره 55 5  شماره 

صفحات  -

تاریخ انتشار 1966